ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,751, issued on Oct. 14, was assigned to The General Hospital Corp. (Boston).

"Metabolic labeling and molecular enhancement of biological materials using bioorthogonal reactions" was invented by Harald C. Ott (Wenham, Mass.), Xi Ren (Malden, Mass.), Jordan P. Bloom (Charlestown, Mass.) and Taufiek Konrad Rajab (Hirrlingen, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present application provides methods of functionalizing an organ or tissue of a mammal by administering a nutrient (e.g., peracetylated N-azido galactosamine Ac4GalNAz) to the mammal or by culturing an organ or tissue in a bioreactor containing such nutrient. The present ap...