ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,472,271, issued on Nov. 18, was assigned to The General Hospital Corp. (Boston).
"HDAC6 inhibitors and imaging agents" was invented by Jacob Hooker (Belmont, Mass.), Changning Wang (Melrose, Mass.), Martin Georg Strebl-Bantillo (Somerville, Mass.) and Johanna Kaarina Rokka (Boston).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are compounds useful for binding to one or more histone deacetylase enzymes (HDACs). The present application further provides radiolabeled compounds useful as a radiotracer for position emission tomography imaging of HDAC. Methods for prepared unlabeled and labeled compounds, diagnostic methods, and methods of trea...