US Patent Issued to The General Hospital on Dec. 9 for "Imaging histone deacetylases with a radiotracer using positron emission tomography" (Massachusetts Inventors)

ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,491,270, issued on Dec. 9, was assigned to The General Hospital Corp. (Boston).

"Imaging histone deacetylases with a radiotracer using positron emission tomography" was invented by Jacob M. Hooker (Charlestown, Mass.), Changning Wang (Acton, Mass.) and Frederick Albert Schroeder (Baltimore, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are histone deacetylase imaging agents for positron emission tomography and related imaging methods using the histone deacetylase imaging agents. The histone deacetylase imaging agents may be a compound of formula (I):wherein R1 is a moiety including a positron emitter; R2 represents hydrogen, or su...