US Patent Issued to The General Hospital, Dana-Farber Cancer Institute, The Broad Institute on Aug. 19 for "Method for predicting HLA-binding peptides using protein structural features" (Massachusetts Inventors)

ALEXANDRIA, Va., Aug. 20 -- United States Patent no. 12,394,502, issued on Aug. 19, was assigned to The General Hospital Corp. (Boston), Dana-Farber Cancer Institute Inc. (Boston) and The Broad Institute Inc. (Cambridge, Mass.).

"Method for predicting HLA-binding peptides using protein structural features" was invented by Nir Hacohen (Boston), Catherine J. Wu (Boston), Siranush Sarkizova (Boston) and Matthew Bakalar (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention discloses a method for predicting peptides that are capable of binding to HLA molecules that incorporate the crystal structure of HLA molecules. An improved HLA-specific peptide docking workflow is used to simu...