US Patent Issued to THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES on July 29 for "Synthesis of DNA molecules in in vitro enzymatic systems" (Florida Inventor)

ALEXANDRIA, Va., July 30 -- United States Patent no. 12,371,725, issued on July 29, was assigned to THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES (Miami).

"Synthesis of DNA molecules in in vitro enzymatic systems" was invented by Fenfei Leng (Palmetto Bay, Fla.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method, which synthesizes closed circular single-stranded and double-stranded DNA molecules using in vitro enzymatic systems, is described. Circular single-stranded DNA molecules and double-stranded DNA molecules (e.g., relaxed, or supercoiled) with various sizes can be synthesized. Unwanted DNA molecules, e.g., unligated oligomers, can be removed by exonucleases, such as T5 exonuclease, T7 exo...