US Patent Issued to The Florida International University Board of Trustees on Dec. 16 for "DRP-1 inhibitors as therapeutic agents" (Florida Inventors)

ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,371, issued on Dec. 16, was assigned to The Florida International University Board of Trustees (Miami).

"DRP-1 inhibitors as therapeutic agents" was invented by Kim Tieu (Miami), Adel Nefzi (Miami) and Stephen Black (Miami).

According to the abstract* released by the U.S. Patent & Trademark Office: "The subject invention provides compounds as Drp1 inhibitors, compositions comprising a Drp1 inhibitor, and methods for inhibiting Drp1 protein using the Drp1 inhibitors. Further provided are methods for treating and/or preventing a disease or condition associated with mitochondrial dysfunction, oxidative stress, inflammation and/or autophagy. Advantageously, the compounds and composit...