ALEXANDRIA, Va., June 25 -- United States Patent no. 12,336,531, issued on June 24, was assigned to THE CLEVELAND CLINIC FOUNDATION (Cleveland).

"Portable, ex vivo, normothermic limb perfusion machine" was invented by Bahar Bassiri Gharb (Westlake, Ohio), Antonio Rampazzo (Cleveland) and Varun Lingaiah Kopparthy (Cleveland).

According to the abstract* released by the U.S. Patent & Trademark Office: "A portable, ex vivo perfusion system for preserving detached biological tissue includes a receptacle for housing the tissue in a normothermic environment, a perfusion core to pump perfusate through the tissue via at least one conduit, at least one detection device to measure parameters during perfusion, and at least one parameter control devic...