US Patent Issued to The Chinese University of Hong Kong on Sept. 16 for "Methylation pattern analysis of haplotypes in tissues in a DNA mixture" (Chinese Inventors)

ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,416,049, issued on Sept. 16, was assigned to The Chinese University of Hong Kong (Shatin, Hong Kong).

"Methylation pattern analysis of haplotypes in tissues in a DNA mixture" was invented by Yuk-Ming Dennis Lo (Kowloon, China), Kwan Chee Chan (Jordan, China), Rossa Wai Kwun Chiu (Shatin, China), Peiyong Jiang (Shatin, China) and Kun Sun (Shatin, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "Systems, apparatuses, and method are provided for determining the contributions of different tissues to a biological sample that includes a mixture of cell-free DNA molecules from various tissues types, e.g., as occurs in plasma or serum and other body fluids...