ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,452, issued on Oct. 21, was assigned to THE CHILDREN'S MEDICAL CENTER Corp. (Boston).

"Methods and compositions relating to anti-PD1 antibody reagents" was invented by Frederick W. Alt (Cambridge, Mass.), Ming Tian (Boston) and Hwei-Ling Cheng (Northborough, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are novel anti-PD1 antibody reagents (e.g., antibodies, antigen-binding fragments thereof, and/or chimeric antigen receptors). Also described herein antibody-drug conjugates or kits comprising the disclosed antibody reagents, as well as methods of treating cancer by administering the disclosed antibody reagents."

The patent w...