ALEXANDRIA, Va., June 18 -- United States Patent no. 12,325,880, issued on June 10, was assigned to THE BROAD INSTITUTE INC. (Cambridge, Mass.).
"Identification of PDE3 modulator responsive cancers" was invented by Xiaoyun Wu (Cambridge, Mass.) and Heidi Greulich (Cambridge, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure features methods for identifying pateints having a hyperproliferative disease, disorder, or condition responsive to phosphodiesterase 3 (PDE3) and schlafen family member 12 (SLFN12) complex formation. The hyperproliferative disease, disorder, or condition may be cancer in a patient including glioblastoma, melanoma, ovarian cancer, cervical cancer, sarcoma, or hem...