US Patent Issued to THE BROAD INSTITUTE, THE GENERAL HOSPTIAL on July 29 for "Systems and methods for MHC class II epitope prediction" (Massachusetts Inventors)

ALEXANDRIA, Va., July 30 -- United States Patent no. 12,374,423, issued on July 29, was assigned to THE BROAD INSTITUTE INC (Cambridge, Mass.) and THE GENERAL HOSPTIAL Corp. (Boston).

"Systems and methods for MHC class II epitope prediction" was invented by Ramnik Xavier (Boston), Daniel B. Graham (Cambridge, Mass.) and Chengwei Luo (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A system and method for prediction of immunodominant epitopes is provided herein. MHCII peptidomics was used to discover complex bacterial epitopes and host antigen processing pathways. Novel insights into the features of antigenicity are leveraged to build an algorithm for prediction of immunodominant epitopes. Use...