US Patent Issued to The Broad Institute, President and Fellows of Harvard College on Oct. 7 for "Methods and compositions for prime editing RNA" (Massachusetts Inventors)

ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,435,330, issued on Oct. 7, was assigned to The Broad Institute Inc. (Cambridge, Mass.) and President and Fellows of Harvard College (Cambridge, Mass.).

"Methods and compositions for prime editing RNA" was invented by David R. Liu (Cambridge, Mass.), Andrew Vito Anzalone (Cambridge, Mass.), James William Nelson (Cambridge, Mass.) and Peter J. Chen (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides compositions and methods for the targeted modification of RNA molecules by RNA prime editing. The compositions and methods may be conducted invitro or in vivo within cells (e.g., human cells) for the therapeutic corr...