US Patent Issued to The Broad Institute, President and Fellows of Harvard College on Feb. 10 for "Amplicon-based sequencing using dna spike-ins" (Massachusetts Inventors)

ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,952, issued on Feb. 10, was assigned to The Broad Institute Inc. (Cambridge, Mass.) and President and Fellows of Harvard College (Cambridge, Mass.).

"Amplicon-based sequencing using dna spike-ins" was invented by Pardis Sabeti (Cambridge, Mass.), Bronwyn Macinnis (Cambridge, Mass.), Erica Normandin (Cambridge, Mass.), Katie Siddle (Cambridge, Mass.), Steven Reilly (Cambridge, Mass.), Matthew Bauer (Cambridge, Mass.) and Kim Lagerborg (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Embodiments disclosed herein provide methods of using synthetic DNA spike-ins (SDSIs) to detect, prevent, and quantify contamination in amplicon sequencin...