US Patent Issued to The Broad Institute, President and Fellows of Harvard College on April 22 for "Methods and compositions for prime editing nucleotide sequences" (Massachusetts Inventors)

ALEXANDRIA, Va., June 6 -- United States Patent no. 12,281,303, issued on April 22, was assigned to The Broad Institute Inc. (Cambridge, Mass.) and President and Fellows of Harvard College (Cambridge, Mass.).

"Methods and compositions for prime editing nucleotide sequences" was invented by David R. Liu (Cambridge, Mass.), Andrew Vito Anzalone (Cambridge, Mass.) and James William Nelson (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods are provided herein for conducting prime editing of a target DNA molecule (e.g., a genome) that enables the incorporation of a nucleotide change and/or targeted mutagenesis. The compositions include fusion proteins comprising nucleic acid...