ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,687, issued on Oct. 28, was assigned to THE BROAD INSTITUTE INC. (Cambridge, Mass.) and Massachusetts Institute of Technology (Cambridge, Mass.).

"Functional genomics using CRISPR-Cas systems, compositions, methods, knock out libraries and applications thereof" was invented by Feng Zhang (Cambridge, Mass.), Neville Espi Sanjana (Cambridge, Mass.) and Ophir Shalem (Albany, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention generally relates to compositions, methods applications and screens used in functional genomics that focus on gene function in a cell and that may use vector systems and other aspects related to Clustered R...