US Patent Issued to The Broad Institute, Massachusetts Institute of Technology on May 13 for "Systems, methods, and compositions for targeted nucleic acid editing" (Massachusetts Inventor)

ALEXANDRIA, Va., June 12 -- United States Patent no. 12,297,436, issued on May 13, was assigned to The Broad Institute Inc. (Cambridge, Mass.) and Massachusetts Institute of Technology (Cambridge, Mass.).

"Systems, methods, and compositions for targeted nucleic acid editing" was invented by Feng Zhang (Cambridge, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides for systems, methods, and compositions for targeting and editing nucleic acids. In particular, the invention provides non-naturally occurring or engineered DNA-targeting systems comprising a DNA-targeting Cpf1 protein, at least one guide molecule, and at least one cytidine deaminase protein or catalytic domain thereof."

The...