US Patent Issued to THE BRIGHAM AND WOMEN'S HOSPITAL on Dec. 30 for "Generation regulatable fusogenic oncolytic herpes simplex virus type 1 virus and methods of use" (Massachusetts Inventor)

ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,509,662, issued on Dec. 30, was assigned to THE BRIGHAM AND WOMEN'S HOSPITAL INC..

"Generation regulatable fusogenic oncolytic herpes simplex virus type 1 virus and methods of use" was invented by Feng Yao (Southborough, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Malignant tumors that are resistant to conventional therapies represent significant therapeutic challenges. An embodiment of the present invention provides a new generation regulatable fusogenic oncolytic herpes simplex virus-1 that is more effective at selective killing target cells, such as tumor cells. In various embodiments presented herein, the oncolytic virus described herein is...