ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,525,361, issued on Jan. 13, was assigned to The Board of Trustees of the Leland Stanford Junior University (Stanford, Calif.).

"Systems and methods for modelling physiologic function using a combination of models of varying detail" was invented by Ryan Leonard Spilker (Arlington, Mass.) and Charles Anthony Taylor Jr. (Atherton, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Computational methods are used to create cardiovascular simulations having desired hemodynamic features. Cardiovascular modeling methods produce descriptions of blood flow and pressure in the heart and vascular networks. Numerical methods optimize and solve nonlinear equations...