US Patent Issued to Texas Tech University System on July 1 for "System and method for solution phase gap peptide synthesis" (Texas Inventors)

ALEXANDRIA, Va., July 3 -- United States Patent no. 12,344,632, issued on July 1, was assigned to Texas Tech University System (Lubbock, Texas).

"System and method for solution phase gap peptide synthesis" was invented by Guigen Li (Lubbock, Texas) and Cole Seifert (Lubbock, Texas).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed is a system and method for Fmoc/tBu solution-phase peptide synthesis including the development of a new benzyl-type GAP protecting group, and related uses thereto. This novel GAP protecting group is utilized in place of a polymer support, facilitating C to N Fmoc peptide synthesis without chromatography, recrystallization, or polymer supports. The GAP group can be added and r...