ALEXANDRIA, Va., April 9 -- United States Patent no. 12,269,809, issued on April 8, was assigned to Temple University-Of The Commonwealth System of Higher Education (Philadelphia).

"5-hydroxytryptamine receptor 7 activity modulators and their method of use" was invented by Daniel J. Canney (Ambler, Pa.), Benjamin E. Blass (Eagleville, Pa.), Rong Gao (Eugene, Ore.) and Magid Abou-Gharbia (Exton, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of 5-hydroxytryptamine receptor 7 activity."

The patent was filed on Nov. 2, 2021, un...