ALEXANDRIA, Va., June 18 -- United States Patent no. 12,324,869, issued on June 10, was assigned to TEI BIOSCIENCES INC. (Boston).

"Perforated tissue graft" was invented by Kevin Cornwell (Holliston, Mass.) and Kenneth James (Barton, Vt.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A tissue graft for soft tissue repair or reconstruction comprising a sheet of a biopolymer-based matrix having a plurality of small perforations and a plurality of large perforations. The small perforations are sized to facilitate clotting and granulation tissue development within the perforations which, in turn, facilitates revascularization and cell repopulation in the patient. The large perforations are sized to reduce the oc...