US Patent Issued to TECLISON on July 8 for "Compositions and methods for immune-mediated cancer therapy" (New Jersey Inventor)

ALEXANDRIA, Va., July 9 -- United States Patent no. 12,350,275, issued on July 8, was assigned to TECLISON INC. (Princeton, N.J.).

"Compositions and methods for immune-mediated cancer therapy" was invented by Ruey-min Lee (Short Hills, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are methods and compositions for enhancing an immune response to a solid tumor in a subject. In some embodiments, a method comprises: (a) administering to the subject a hypoxia-activated bioreductive agent (HABA); (b) inducing hypoxia by (i) administering a hypoxia-inducing agent to the subject or (ii) embolizing one or more blood vessels supplying the solid tumor; and (c) administering an immune checkpoint i...