ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,448,639, issued on Oct. 21, was assigned to TECHNISCHE UNIVERSITAT WIEN (Vienna).

"Methods for producing heme peroxidases" was invented by Diana Humer (Vienna), Oliver Spadiut (Vienna) and Julian Ebner (Vienna).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides methods for producing a heme pe-roxidase from inclusion bodies (IBs) comprising the steps of: providing the heme peroxidase in the form of IBs, solubilizing said IBs, transferring said solubilized IBs into a refolding buffer to obtain a refolding mix, adding a heme cofactor to said refolding mix, wherein the addition of the heme cofactor to the refolding mix is distribut...