ALEXANDRIA, Va., June 12 -- United States Patent no. 12,296,017, issued on May 13, was assigned to Tambo Inc. (San Francisco).
"Bioorthogonal compositions" was invented by Jose Manuel Mejia Oneto (San Francisco), Nathan Yee (San Francisco), Maksim Royzen (San Francisco), Sangeetha Srinivasan (San Francisco) and Ethan Miller (San Francisco).
According to the abstract* released by the U.S. Patent & Trademark Office: "Cyclooctene conjugates of therapeutic or diagnostic agents have improved aqueous solubility and can release the agents upon contact with a tetrazine-containing biomaterial. The cyclooctene conjugates provide site-selective delivery of agents at the location of the tetrazine-containing biomaterial in a subject. The compositions ...