ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,485,136, issued on Dec. 2, was assigned to Takeda Pharmaceuticals U.S.A. Inc. (Cambridge, Mass.).
"Methods for the treatment of trinucleotide repeat expansion disorders associated with MLH3 activity" was invented by Nessan Anthony Bermingham (Cambridge, Mass.), Brian R. Bettencourt (Cambridge, Mass.) and Peter Edward Bialek (Cambridge, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure features useful compositions and methods to treat repeat expansion disorders, e.g., in a subject in need thereof. In some aspects, the compositions and methods described herein are useful in the treatment of disorders associated with MLH3 activity....