ALEXANDRIA, Va., Nov. 25 -- United States Patent no. 12,479,798, issued on Nov. 25, was assigned to Takeda Pharmaceutical Co. Ltd. (Osaka, Japan).
"Method for producing pyrrolidine compound" was invented by Atsuko Nishiguchi (Osaka, Japan) and Yoshihiro Banno (Kanagawa, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a production method suitable for industrial production of (2S,3S)-3-amino-2-(3-bromo-2-fluorobenzyl)pyrrolidine having a protecting group at the 1-position.The present invention is a method for producing N-[(4-methylphenyl)sulfonyl]-L-phenylalanine salt of (2S,3S)-3-amino-2-(3-bromo-2-fluorobenzyl)pyrrolidine having a protecting group at the 1-position, which ...