US Patent Issued to Takeda Pharmaceutical on May 13 for "Method for measuring alpha value of muscarinic M1 receptor positive allosteric modulators" (Japanese Inventors)

ALEXANDRIA, Va., June 12 -- United States Patent no. 12,298,319, issued on May 13, was assigned to Takeda Pharmaceutical Co. Ltd. (Osaka, Japan).

"Method for measuring alpha value of muscarinic M1 receptor positive allosteric modulators" was invented by Haruhide Kimura (Kanagawa, Japan), Yuu Sako (Kanagawa, Japan), Satoru Matsuda (Kanagawa, Japan), Yuji Shimizu (Kanagawa, Japan), Emi Kurimoto (Kanagawa, Japan) and Takao Mandai (Kanagawa, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a useful and efficient screening method for finding a cholinergic muscarinic M1 receptor positive allosteric modulator (M1PAM) with reduced cholinergic side effects. The present invention als...