ALEXANDRIA, Va., June 18 -- United States Patent no. 12,325,714, issued on June 10, was assigned to Takeda Pharmaceutical Co. Ltd. (Osaka, Japan).
"Compositions of thienopyrimidine derivatives" was invented by Kazuhiro Miwa (Osaka, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a production method of a thienopyrimidine derivative or a salt thereof which has a gonadotropin releasing hormone (GnRH) antagonistic action with high quality in high yield. The present invention provides a method of producing a thienopyrimidine derivative, which comprises reacting 6-(4-aminophenyl)-1-(2,6-difluorobenzyl)-5-dimethylaminomethyl-3-(6-methoxypyridazin-3-yl)thieno[2,3-d]pyrimidine-2,4(...