ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,492,390, issued on Dec. 9, was assigned to Takeda Pharmaceutical Co. Ltd. (Osaka, Japan).
"Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof" was invented by Meinhard Hasslacher (Vienna), Christian Fiedler (Vienna) and Artur Mitterer (Orth/Donau, Austria).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods for purifying recombinant A Disintegrin-like and Metallopeptidase with Thrombospondin Type 1 Motif 13 (ADAMTS13) protein from a sample. The method comprises enriching for ADAMTS13 protein by chromatographically contacting the sample with hydroxyapatite under conditions that allow ADAMTS13 protei...