ALEXANDRIA, Va., June 9 -- United States Patent no. 12,286,479, issued on April 29, was assigned to Takeda Pharmaceutical Co. Ltd. (Osaka, Japan).

"Treatment with anti-Alpha4Beta7 antibody" was invented by Irving H. Fox (Wellesley, Mass.), Catherine Scholz (Woburn, Mass.), Erica Helen Jenkins (Cambridgeshire, Great Britain) and Maria Rosario (Mystic, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Antibody formulations are described comprising a mixture of an anti-Alpha4Beta7 antibody, an antioxidant or chelator, and at least one free amino acid. The disclosed formulations may have improved stability, reduced aggregate formation, or both. The present invention further provides a safe dosing regimen of t...