ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,454,721, issued on Oct. 28, was assigned to Takara Bio USA Inc. (San Jose, Calif.).
"Template switch-based methods for producing a product nucleic acid" was invented by Craig Betts (Mountain View, Calif.), Andrew Alan Farmer (Los Altos, Calif.) and Nathalie Bolduc (Mountain View, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are methods of producing a product nucleic acid. The methods include combining a template deoxyribonucleic acid (DNA), a polymerase, a template switch oligonucleotide, and dNTPs into a reaction mixture. The components are combined into the reaction mixture under conditions sufficient to produce a product nucleic aci...