ALEXANDRIA, Va., July 16 -- United States Patent no. 12,359,177, issued on July 15, was assigned to Takara Bio Inc. (Shiga, Japan).
"DNA polymerase mutant suited to nucleic acid amplification from RNA" was invented by Takashi Uemori (Otsu, Japan), Hiroyuki Matsumoto (Santa Clara, Calif.), Kensuke Saito (Kusatsu, Japan) and Miwa Akitomo (Kyoto, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are: a DNA polymerase mutant having reverse transcriptase activity, the DNA polymerase mutant including a sequence consisting of twelve specific amino acids A1-A12, wherein the DNA polymerase mutant having reverse transcriptase activity is characterized in that the A3 and/or A10 amino acid is substituted by ...