US Patent Issued to TAIRX on June 3 for "Formulations with enhanced SN-38 solubility and oral absorption" (American, Taiwanese Inventors)

ALEXANDRIA, Va., June 4 -- United States Patent no. 12,318,372, issued on June 3, was assigned to TAIRX INC. (Taipei, Taiwan).

"Formulations with enhanced SN-38 solubility and oral absorption" was invented by Yi-Wen Chu (New Taipei, Taiwan) and Du-Shieng Chien (Guilford, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Formulations with enhanced SN-38 solubility and oral absorption. In one embodiment, a formulation or a pharmaceutical composition comprises (a) 7-Ethyl-10-hydroxy-camptothecin (SN-38); and (b) a mixture of pharmaceutically acceptable excipients comprising (i) N-Methylpyrrolidone; and (ii) Vitamin E TPGS or a copolymer, the copolymer being 50/50 poly(lactic-co-glycolic acid), or 75/25 poly(...