ALEXANDRIA, Va., July 9 -- United States Patent no. 12,349,665, issued on July 8, was assigned to TAIPEI VETERANS GENERAL HOSPITAL (Taipei, Taiwan) and NATIONAL YANG-MING UNIVERSITY (Taipei, Taiwan).
"Animal model for hepatocellular carcinoma and uses thereof" was invented by Jaw-Ching Wu (Taipei, Taiwan) and Yu-Wei Chiou (Taipei, Taiwan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides an animal model for hepatocellular carcinoma and uses thereof. The genome of the animal model includes a hepatitis B virus genome and a single set of endogenous miR-122 that is partially deleted. Due to the early and high incidence of spontaneous hepatocellular carcinoma in the animal model and its abnorma...