ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,483, issued on Sept. 30, was assigned to SystImmune Inc. (Redmond, Wash.).

"Bispecific tetravalent antibodies and methods of making and using thereof" was invented by Zeren Gao (Bellevue, Wash.), Phil Tan (Bellevue, Wash.), Brian R. Kovacevich (Bellevue, Wash.), Blair R. Renshaw (Bellevue, Wash.), Jeffrey B. Adamo (Bellevue, Wash.), Nge Sze Amanda Mak (Bellevue, Wash.), Shi Zhuo (Chengdu, China), Lan Chen (Chengdu, China) and Yi Zhu (Chengdu, China).

According to the abstract* released by the U.S. Patent & Trademark Office: "A bispecific tetravalent antibody comprising an IgG having a pair of heavy chains and a pair of light chains, and two scFv components being connected to eit...