ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,545,688, issued on Feb. 10, was assigned to SYSTIMMUNE INC. (Redmond, Wash.).
"Camptothecin derivative and conjugate thereof" was invented by Yi Zhu (Sichuan, China), Weili Wan (Sichuan, China), Shi Zhuo (Sichuan, China), Wei Zhang (Sichuan, China), Yiying Zhang (Sichuan, China) and Tao K. Xu (Sichuan, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "An antitumor pharmaceutical camptothecin derivative and an antibody-drug conjugate thereof. By means of a series of molecular structure modifications, an optimal camptothecin antitumor drug is obtained, so as to be more suitable as a drug for antibody conjugation."
The patent was filed on Sept. 17, 202...