ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,474,341, issued on Nov. 18, was assigned to SYSMEX Corp. (Kobe, Japan).

"Method for determining onset risk of cardiovascular disease in subject, and method for determining vascular calcification in subject" was invented by Maria Kiriyama (Kobe, Japan), Eiya Tamada (Kobe, Japan), Elnaz Nakhaei (Kobe, Iran) and Mami Onishi (Kobe, Japan).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed is a method of determining onset risk of cardiovascular disease in a subject, the method comprising: capturing, on a solid phase, an extracellular vesicle derived from a blood sample collected from the subject; and measuring alkaline phosphatase activity of the extrac...