US Patent Issued to Synthena on June 3 for "Tricyclo-DNA nucleoside precursors and processes for preparing the same" (Swiss Inventors)

ALEXANDRIA, Va., June 4 -- United States Patent no. 12,319,667, issued on June 3, was assigned to Synthena AG (Bern, Switzerland).

"Tricyclo-DNA nucleoside precursors and processes for preparing the same" was invented by Branislav Dugovic (Bern, Switzerland) and Reto Bertolini (Liebefeld, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a process for preparing tc-DNA nucleoside precursors, the resulting tc-DNA nucleosides, and oligonucleotides comprising such tc-DNA nucleosides. In an embodiment of the invention, the process includes use of a carbene precursor. In an embodiment, the invention includes processes for preparing a tc-DNA nucleoside precursor of Formula ...