ALEXANDRIA, Va., June 16 -- United States Patent no. 12,303,489, issued on May 20, was assigned to Synact Pharma APS (Holte, Denmark).
"Combination treatment of arthritic disease" was invented by Thomas Engelbrecht Nordkild Jonassen (Holte, Denmark).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a composition comprising, separately or together, methotrexate (MTX) and (E)-N-trans-{3-[1-(2-nitrophenyl)-1H-pyrrol-2-yl]-allylidene}-aminoguanidinium acetate (AP1189), or pharmaceutically acceptable derivatives thereof, for use in a method of treating an arthritis disease, such as rheumatoid arthritis."
The patent was filed on May 7, 2020, under Application No. 17/609,849.
*For fur...