ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,440,469, issued on Oct. 14, was assigned to Syddansk Universitet (Odense M, Denmark).

"P-gp inducers as protectors against chemotherapy-induced side effects, such as peripheral neuropathy (CIPN) and hair loss" was invented by Tore Bjerregaard Stage (Odense SV, Denmark).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to compositions comprising a P-gp inducer, for topical use in preventing one or more side effects of chemotherapeutics, which chemotherapeutics are transported out of cells by P-gp. Especially chemotherapy-induced peripheral neuropathy (CIPN) is a relevant side effect to treat/avoid, since CIPN may be a dose limit...