ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,642, issued on Sept. 30, was assigned to SUZHOU RIBO LIFE SCIENCE Co. LTD. (Jiangsu, China).
"Nucleic acid, composition and conjugate comprising the same, preparation method and use thereof" was invented by Hongyan Zhang (Suzhou, China), Shan Gao (Suzhou, China), Daiwu Kang (Suzhou, China) and Lina Kong (Suzhou, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are a siRNA for inhibiting the expression of an angiopoietin-like protein 3 (ANGPTL3) gene, and a pharmaceutical composition and a conjugate comprising the siRNA; wherein each nucleotide in the siRNA is independently a modified or unmodified nucleotide, and the siRNA comprises a ...