ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,496,347, issued on Dec. 16, was assigned to SUZHOU RIBO LIFE SCIENCE Co. LTD. (Jiangsu, China).
"Nucleic acid, composition and conjugate containing nucleic acid, preparation method therefor and use thereof" was invented by Hongyan Zhang (Jiangsu, China), Shan Gao (Jiangsu, China) and Daiwu Kang (Jiangsu, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are an siRNA for inhibiting the expression of the apolipoprotein C3 gene, and a pharmaceutical composition and a conjugate containing the siRNA. Each nucleotide in the siRNA is, respectively and independently, a modified or unmodified nucleotide; the siRNA contains a sense strand an anti-sens...