ALEXANDRIA, Va., June 5 -- United States Patent no. 12,274,752, issued on April 15, was assigned to SUZHOU RIBO LIFE SCIENCE Co. LTD. (Kunshan, China).
"Nucleic acid, composition and conjugate containing same, preparation method, and use thereof" was invented by Hongyan Zhang (Suzhou, China), Shan Gao (Suzhou, China) and Daiwu Kang (Suzhou, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides a siRNA for inhibiting the expression of apolipoprotein C3 (ApoC3) gene, and a pharmaceutical composition and a conjugate comprising the siRNA; wherein each nucleotide in the siRNA is independently a modified nucleotide, and the siRNA comprises a sense strand an antisense strand; the sens...