ALEXANDRIA, Va., June 6 -- United States Patent no. 12,281,088, issued on April 22, was assigned to SUZHOU FUDE ZHAOFENG BIOCHEMICAL TECHNOLOGY Co. LTD (Suzhou, China).
"Process for the synthesis of vortioxetine" was invented by Lihua Zhou (Suzhou, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a process for the synthesis of Vortioxetine (I) or a pharmaceutically acceptable salt thereof. This process is accomplished by using a catalytic system consisting of a copper salt and an organic ligand, which can promote the formation of both C-N and C-S bond in one-pot, giving rise to an efficient, simple and industrially viable synthetic route for Vortioxetine."
The patent was...