US Patent Issued to SUNSHINE GUOJIAN PHARMACEUTICAL (SHANGHAI) on Aug. 12 for "Anti-HER2/PD1 bispecific antibody" (Chinese Inventors)

ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,384,853, issued on Aug. 12, was assigned to SUNSHINE GUOJIAN PHARMACEUTICAL (SHANGHAI) Co. LTD. (Shanghai).

"Anti-HER2/PD1 bispecific antibody" was invented by Zhenping Zhu (Shanghai), Haomin Huang (Shanghai) and Changling Gu (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are an anti-HER2/PD1 bispecific antibody, preparation method, and antitumor application. Specifically, a single-chain variable fragment scFv and an immunoglobulin antibody IgG are connected by means of a peptide linker to obtain a bispecific antibody; the bispecific antibody can simultaneously target the tumor cell surface molecule HER2 antigen and T lymphocyte surfa...