ALEXANDRIA, Va., April 2 -- United States Patent no. 12,263,167, issued on April 1, was assigned to Sumitomo Pharma Co. Ltd. (Osaka, Japan).
"Optically active azabicyclo ring derivative" was invented by Seiji Kamioka (Osaka, Japan), Hitoshi Ban (Osaka, Japan), Naoaki Shimada (Osaka, Japan), Wataru Hirose (Osaka, Japan), Akihiko Arakawa (Odawara, Japan), Kazuto Yamazaki (Ikoma, Japan) and Kenjiro Hira (Osaka, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The compound of formula (1a) wherein p is 1 or 2, R1-R4 are hydrogen atom or the like, and a-d are 1 or 2, or a pharmaceutically acceptable salt thereof, which has an antitumor effect by inhibiting the binding between a MLL fusion protein that is infus...