ALEXANDRIA, Va., Aug. 20 -- United States Patent no. 12,391,716, issued on Aug. 19, was assigned to Sumitomo Chemical Co. Ltd. (Chuo-ku, Japan).
"Process of preparing nucleic acid oligomer" was invented by Takuya Miyagawa (Osaka, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides an efficient process for preparing a nucleic acid oligomer, that is, a process for preparing a nucleic acid having a phosphate triester bond effectively by oxidizing a nucleic acid precursor having a phosphite triester bond. Specifically, the present invention provides a process for preparing a nucleic acid compound having at its 5'-terminus a nucleotide represented by formula (I) by a phosphoramidit...