ALEXANDRIA, Va., March 19 -- United States Patent no. 12,251,700, issued on March 18, was assigned to STRATEC SE (Birkenfeld, Germany).

"Thermal cycler" was invented by Bernd Grohbuhl (Ettlingen, Germany) and Martin Trump (Pforzheim, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "A system for thermal cycling, comprising at least one separate vessel holder for taking up a reaction vessel providing a contact surface for the reaction vessel, wherein the vessel holder is surrounded by individual liquid channels for cooling and at least one electrical heater is attached to the at least one separate vessel holder; and a multilayer liquid port for attachment of at least one vessel holder for providing the c...