US Patent Issued to STICHTING WAGENINGEN RESEARCH on Sept. 9 for "Haploid embryogenesis" (Dutch, Chinese, Spanish Inventors)

ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,408,605, issued on Sept. 9, was assigned to STICHTING WAGENINGEN RESEARCH (Wageningen, Netherlands).

"Haploid embryogenesis" was invented by Kimberly Boutilier (De Meern, Netherlands), Gerrit Cornelis Angenent (Wageningen, Netherlands), Mercedes Soriano Castan (Monzon, Spain) and Li Hui (Beijing).

According to the abstract* released by the U.S. Patent & Trademark Office: "A switch to haploid embryogenesis is controlled by the activity of histone deacetylases (HDACs). Blocking HDAC activity with HDAC inhibitors (HDACi), e.g., trichostatin A (TSA), in Brassica napus, B. rapa, Arabidopsis thaliana, and Capsicum annuum male gametophytes leads to a large increase in the proportion of cel...