ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,458, issued on Sept. 30, was assigned to STEMRIM INC. (Osaka, Japan) and OSAKA UNIVERSITY (Osaka, Japan).
"Therapeutic agent for psoriasis" was invented by Katsuto Tamai (Osaka, Japan), Takashi Shimbo (Osaka, Japan) and Takehiko Yamazaki (Osaka, Japan).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present inventors discovered that an HMGB1 fragment peptide having a specific amino acid sequence exhibits an effect of suppressing erythema, scaling (desquamation), and thickening (infiltration) of the skin in an animal model of psoriasis. Based on these findings, pharmaceutical compositions for the prevention and/or treatment of psoriasis, which com...